Provigil package insert
Provigil. PHARMACY PRE-AUTHORIZATION CRITERIA DRUG Provigil (modafinil) REFERENCES 1. The molecular formula is C15H15NO2S and the molecular weight is 273.35. PROVIGIL (modafinil) [package insert]. National Heart, Lung, and Blood Institute. This derivative can be acetylated, hydroxylated and - glucuronidated. Modafinil is a white to off-white, crystalline powder that is practically insoluble in water and cyclohexane. It is soluble in water and sparingly soluble in methanol and practically insoluble in ethanol Provigil (modafinil) is a medication that promotes wakefulness. NUVIGIL has not been studied in pediatric patients in any setting and is not approved for use in pediatric patients for any indication. National Institutes of Health. Nuvigil [package insert]. Two major metabolites of modafinil, modafinil acid and modafinil sulfone, do not appear to contribute to the CNS-activating properties of modafinil. The sleep disorders these drugs can help treat include. Provigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. In cases where the time to onset was reported, serious rash occurred 1 day to 2 months after initiation of treatment,. Provigil is a stimulant prescribed to increase wakefulness in patients with excessive sleepiness related to narcolepsy, shiftwork sleep disorder, and obstructive sleep apnea/hypopnea syndrome.Common side effects of Provigil are: headache, dizziness, upper respiratory tract infection, ; nausea, diarrhea, nervousness, anxiety, agitation,. Adderall ® 7.5 mg and 10 mg contain FD&C Blue #1 Aluminum Lake as a color additive. NUVIGIL (armodafinil) [package insert]. Additional labeling revisions were made to the CLINICAL PHARMACOLOGY, PRECAUTIONS, and PATIENT PACKAGE INSERT sections See full prescribing provigil package insert information for complete boxed warning. On Thursday, Feb. Provigil package insert. Evaluation of the Safety of Modafinil for Treatment of Excessive Sleepiness Xyrem (sodium oxybate) is a CNS depressant. In clinical trials of modafinil, the incidence of rash resulting in discontinuation was approximately 0.8% (13 per 1,585) in pe diatric. Although the drug was successful.The State of Washington is part of a group of states that have reached a settlement agreement with Cephalon, Inc., Teva Pharmaceutical Industries, Ltd., Teva Pharmaceuticals USA, Inc., and Barr Pharmaceuticals, Inc. Pharmacokinetics Modafinil is a racemic compound whose enantiomers have different pharmacokinetics (e.g. Nuvigil may interact with cyclosporine, propranolol, omeprazole, rifampin, sedatives, seizure medications, antidepressants, or antibiotics.Tell your doctor all medications you use. • Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Sleep apnea: how is sleep apnea treated? At steady state, total exposure to the l-isomer is approximately three times that for the d-isomer.The trough concentration (Cminss) of circulating modafinil after once daily dosing consists of 90% of the l-isomer and 10% of the d-isomer modafinil and NUVIGIL. PHARMACY PRE-AUTHORIZATION CRITERIA DRUG Provigil (modafinil) REFERENCES 1. References 1. Provigil is approved only for narcolepsy, sleep apnea or for people who work irregular hours, but hidden among those who take it are pockets of healthy Americans taking it just to boost energy and.